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Shigeki Yoshida Selected Research

ulipristal

9/2011Lessons learned from the preclinical drug discovery of asoprisnil and ulipristal for non-surgical treatment of uterine leiomyomas.
11/2010Translational research with progesterone receptor modulator motivated by the use of levonorgestrel-releasing intrauterine system.
5/2010Cell-type specific actions of progesterone receptor modulators in the regulation of uterine leiomyoma growth.
3/2008Progesterone receptor modulator CDB-2914 induces extracellular matrix metalloproteinase inducer in cultured human uterine leiomyoma cells.

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Shigeki Yoshida Research Topics

Disease

11Leiomyoma (Uterine Fibroids)
09/2011 - 02/2005
9Endometriosis
01/2007 - 02/2004
4Neoplasms (Cancer)
04/2022 - 12/2004
2Atherosclerosis
07/2020 - 01/2011
2Bone Resorption
05/2015 - 01/2014
2Uterine Cervical Neoplasms (Cancer of the Cervix)
10/2011 - 12/2004
2Menorrhagia
09/2011 - 11/2010
2Endometrial Neoplasms (Endometrial Cancer)
05/2007 - 10/2006
1Epithelioid Leiomyoma
04/2022
1Chronic Renal Insufficiency
01/2021
1Wounds and Injuries (Trauma)
07/2020
1Male Infertility (Male Sterility)
04/2019
1absence of Vagina
03/2013
1Margins of Excision
10/2011
1Coronary Disease (Coronary Heart Disease)
01/2011
1Myoma
11/2010
1Carcinoma (Carcinomatosis)
10/2008
1Pre-Eclampsia (Preeclampsia)
04/2007
1Ascites
01/2007
1Hemorrhage
01/2007
1Osteosarcoma (Osteogenic Sarcoma)
01/2005
1Autoimmune Diseases (Autoimmune Disease)
11/2004

Drug/Important Bio-Agent (IBA)

7Progesterone Receptors (Progesterone Receptor)IBA
11/2010 - 04/2006
6asoprisnilIBA
09/2011 - 04/2006
5Matrix Metalloproteinases (MMPs)IBA
11/2010 - 04/2006
5Proteins (Proteins, Gene)FDA Link
04/2008 - 02/2005
4ulipristalIBA
09/2011 - 03/2008
4CollagenIBA
11/2010 - 03/2008
3EnzymesIBA
07/2020 - 04/2008
3Metalloproteases (Metalloproteinases)IBA
11/2010 - 03/2008
3ProgesteroneFDA LinkGeneric
11/2010 - 04/2006
3Epidermal Growth Factor (EGF)IBA
11/2010 - 02/2005
3Proliferating Cell Nuclear Antigen (PCNA)IBA
11/2010 - 02/2005
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
05/2010 - 11/2004
3Messenger RNA (mRNA)IBA
03/2008 - 01/2005
2ResveratrolIBA
07/2020 - 01/2011
2LycopeneIBA
05/2015 - 01/2014
2Tissue Inhibitor of Metalloproteinase-2IBA
11/2010 - 04/2008
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2010 - 01/2007
2LigandsIBA
05/2010 - 02/2007
2Estrogens (Estrogen)FDA Link
05/2010 - 04/2006
2Basigin (Extracellular Matrix Metalloproteinase Inducer (EMMPRIN))IBA
04/2008 - 03/2008
2ErbB Receptors (EGF Receptor)IBA
05/2007 - 01/2007
2Matrix Metalloproteinase 1 (Interstitial Collagenase)IBA
10/2006 - 04/2006
2Steroid 17-alpha-Hydroxylase (17 alpha Hydroxylase)IBA
02/2006 - 02/2005
2DNA (Deoxyribonucleic Acid)IBA
02/2005 - 02/2004
1Phosphates (Orthophosphate)IBA
01/2021
1Nitric Oxide (Nitrogen Monoxide)FDA Link
07/2020
1Sirtuin 1IBA
07/2020
1AntioxidantsIBA
07/2020
1PhytochemicalsIBA
04/2019
1atelocollagenIBA
03/2013
1Pharmaceutical PreparationsIBA
09/2011
1Levonorgestrel (Plan B)FDA LinkGeneric
11/2010
1Collagen Type III (Type III Collagen)IBA
11/2010
1AdrenomedullinIBA
11/2010
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
05/2010
1Protein Isoforms (Isoforms)IBA
05/2010
1Cisplatin (Platino)FDA LinkGeneric
10/2008
1Matrix Metalloproteinase 14 (MT1-MMP)IBA
04/2008
1Dihydrotachysterol (AT 10)IBA
04/2008
1Tissue Inhibitor of Metalloproteinase-1IBA
04/2008
1human ERBB2 proteinIBA
05/2007
1AdiponectinIBA
04/2007
1Inhibitor of Apoptosis ProteinsIBA
02/2007
1Caspase 8 (Caspase-8)IBA
02/2007
1TNF-Related Apoptosis-Inducing LigandIBA
02/2007
1Caspase 3 (Caspase-3)IBA
04/2006
1Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA
05/2005
1AcetyltransferasesIBA
04/2005
1TransferasesIBA
04/2005
1N-acetyltransferase 1IBA
04/2005
1cetrorelix (Cetrotide)FDA Link
02/2005
1Bovine Serum AlbuminIBA
02/2005
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
02/2005
1DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA
02/2005
1LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA
02/2005
1DeoxyuridineIBA
02/2005
1Phenolsulfonphthalein (Phenol Red)IBA
02/2005
1Insulin-Like Growth Factor I (IGF-1)IBA
01/2005
1IGF Type 1 Receptor (IGF 1 Receptor)IBA
01/2005
1Estriol (Epiestriol)IBA
01/2005
1CytokinesIBA
11/2004
1Estrogen Receptor betaIBA
06/2004
1Estrogen Receptor alphaIBA
06/2004
1Estrogen ReceptorsIBA
06/2004
1Codon (Codons)IBA
05/2004
1glutathione S-transferase M1IBA
02/2004

Therapy/Procedure

2Hysterectomy
04/2022 - 09/2011
2Radiotherapy
10/2011 - 12/2004
2Laparotomy
01/2007 - 06/2004
1Salpingectomy
04/2022
1Operative Surgical Procedures
03/2013
1Brachytherapy
10/2011
1Oral Administration
09/2011
1Neoadjuvant Therapy
10/2008
1Operative Time
01/2007
1Intra-Arterial Infusions
12/2004
1Drug Therapy (Chemotherapy)
12/2004